Structure of PDB 8a3v Chain B

Receptor sequence
>8a3vB (length=447) Species: 666 (Vibrio cholerae) [Search protein sequence]
IPDAQVDAIKVPPHSLEAEQSVIGGLLLDNERWDTVSEHVMTQDFYSRPH
RLIFDGVKSILEAGKPLDLITLSEYLEQREQLEDVGGFAYLADLAKNTPS
AANINAYAEIVAERALVRNLIGVANEIADAGYDPQGRNAEDLLDLAESKV
FAIAEARTSENEGPKNVDSILERTLERIELLYKTPQDGVTGVNTGFTDLN
KKTAGLQGSDLIIVAARPSMGKTTFAMNLCENAAMEQDKPVLIFSLEMPA
EQIMMRMLASLSRVDQTKIRTGQLDDEDWARISSTMGILMEKKNMYIDDS
SGLTPTEVRSRARRIAREHGGLSLIMVDYLQLMRVPALTDNRTLEIAEIS
RSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLI
MFIYRDEVYHPDSPLKGTAEIIIGKQRNGPIGSVRLTFQGHYSRFDN
3D structure
PDB8a3v The LH-DH module of bacterial replicative helicases is the common binding site for DciA and other helicase loaders.
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B G441 P442 G429 P430
BS02 ADP B S231 G233 K234 T235 Q278 Y341 F450 G452 H453 S219 G221 K222 T223 Q266 Y329 F438 G440 H441
BS03 MG B T235 D340 Y341 T223 D328 Y329
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006269 DNA replication, synthesis of primer
Cellular Component
GO:0005829 cytosol
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a3v, PDBe:8a3v, PDBj:8a3v
PDBsum8a3v
PubMed36762863
UniProtA0A085R2T8

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