Structure of PDB 7zvj Chain B

Receptor sequence
>7zvjB (length=587) Species: 9606 (Homo sapiens) [Search protein sequence]
KCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQILA
TLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPA
NLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGPWPA
LGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNA
VIKQNPFLVYQLPCFWNVQLQCVSDLKVIHWNKHVEFFRNLYLTFLEYDG
NLLRRELFGCPSEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLY
FLHYEYEPAADSTDVTLVAQLSMDRLQMLEAICKHWEGPISLALYLSDAE
AQQFLRYAQGSEVLMSRHNVGYHIVYKEGQFYPVNLLRNVAMKHISTPYM
FLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETLRYRLSFPKS
KAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEP
YVVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHA
PSFSNKQYRICLKTLKEEFQQDMSRRYGFAALKYLTA
3D structure
PDB7zvj Structural basis for matriglycan synthesis by the LARGE1 dual glycosyltransferase.
ChainB
Resolution2.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.-.-
2.4.1.-
2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B H705 H708 H546 H549
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7zvj, PDBe:7zvj, PDBj:7zvj
PDBsum7zvj
PubMed36512577
UniProtO95461|LARG1_HUMAN Xylosyl- and glucuronyltransferase LARGE1 (Gene Name=LARGE1)

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