Structure of PDB 7znu Chain B

Receptor sequence

>7znuB (length=556) Species: 359391 (Brucella abortus 2308)

MSLLKIYWRAMQYLAVERTATITMCVASVLVALVTLAEPVLFGRVIQSIS
DKGDIFSPLLMWAALGGFNIMAAVFVARGADRLAHRRRLGVMIDSYERLI
TMPLAWHQKRGTSNALHTLIRATDSLFTLWLEFMRQHLTTVVALATLIPV
AMTMDMRMSLVLIVLGVIYVMIGQLVMRKTKDGQAAVEKHHHKLFEHVSD
TISNVSVVQSYNRIASETQALRDYAKNLENAQFPVLNWWALASGLNRMAS
TFSMVVVLVLGAYFVTKGQMRVGDVIAFIGFAQLMIGRLDQISAFINQTV
TARAKLEEFFQMEDATADRQEPENVADLNDVKGDIVFDNVTYEFPNSGQG
VYDVSFEVKPGQTVAIVGPTGAGKTTLINLLQRVFDPAAGRIMIDGTDTR
TVSRRSLRHAIATVFQDAGLFNRSVEDNIRVGRANATHEEVHAAAKAAAA
HDFILAKSEGYDTFVGERGSQLSGGERQRLAIARAILKDSPILVLDEATS
ALDVETEEKVTQAVDELSHNRTTFIIAHRLSTVRSADLVLFMDKGHLVES
GSFNEL

3D structure

• PDB: 7znu Mechanism of cyclic beta-glucan export by ABC transporter Cgt of Brucella.
• Chain: B
• Resolution: 4.0 Å

Enzymatic activity

• Enzyme Commision number: 7.5.2.3: ABC-type beta-glucan transporter.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ADP	B	Q471 S473	Q471 S473
BS02	ADP	B	F344 G371 A372 G373 K374 T375 T376	F344 G371 A372 G373 K374 T375 T376
BS03	VO4	B	T370 Q416 H528	T370 Q416 H528

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0015441 ABC-type beta-glucan transporter activity
• GO:0016887 ATP hydrolysis activity
• GO:0034040 ATPase-coupled lipid transmembrane transporter activity
• GO:0140359 ABC-type transporter activity

Biological Process

• GO:0006869 lipid transport
• GO:0015775 beta-glucan transport
• GO:0055085 transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:7znu, PDBe:7znu, PDBj:7znu
• PDBsum: 7znu
• PubMed: 36456825
• UniProt: Q2YQ73|NDVA_BRUA2 Beta-(1-->2)glucan export ATP-binding/permease protein NdvA (Gene Name=ndvA)