Structure of PDB 7zlu Chain B

Receptor sequence
>7zluB (length=278) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence]
EHAEINIFSVASGHLYERMLNIMMASVMHHTNHTVKFWFIEQFLSPSFKD
FIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREIWGYKILFLDVLFPLSL
DKVIFVDADQIVRTDMYDLVEHPLDGAPYGFAPMCDSRVEMEGYRFWKTG
YWANYLKGKPYHISALYVVDLQRFRELAAGDRLRQQYHALSADPNSLANL
DQDLPNHMQFTIPIATLPQEWLWCETWCSDETLKDARTIDLCNNPMTKEP
KLDRARRQVPEWTKYDEEIAELARRVRE
3D structure
PDB7zlu A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
ChainB
Resolution2.049 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 U2F B S1207 Y1211 Q1276 W1280 D1302 A1360 N1394 D1396 D1435 C1437 N1438 K1446 S12 Y16 Q81 W85 D107 A165 N199 D201 D240 C242 N243 K251
BS02 CA B D1302 D1304 D1435 D107 D109 D240
BS03 PDO B R1333 E1335 S1424 D1425 R138 E140 S229 D230
Gene Ontology
Molecular Function
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:7zlu, PDBe:7zlu, PDBj:7zlu
PDBsum7zlu
PubMed37822503
UniProtG0SB58

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