Structure of PDB 7zjp Chain B

Receptor sequence
>7zjpB (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]
RSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFVHIGHNHPLLESVDIRQIY
DKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVTSQYE
SSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMI
NFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSE
HGAQHHIYRLVKD
3D structure
PDB7zjp Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead MSC-4106 .
ChainB
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JJU B F221 V240 F290 V308 K336 M358 C359 M362 I387 F407 F13 V32 F77 V95 K123 M145 C146 M149 I174 F194
External links
PDB RCSB:7zjp, PDBe:7zjp, PDBj:7zjp
PDBsum7zjp
PubMed35763499
UniProtP28347|TEAD1_HUMAN Transcriptional enhancer factor TEF-1 (Gene Name=TEAD1)

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