Structure of PDB 7zg9 Chain B

Receptor sequence
>7zg9B (length=294) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
TQQEKEFLESYPQNCPPDALPGTPGNLDSAQEKALAELRKLLEDAGFIER
LDDSTLLRFLRARKFDVQLAKEMFENCEKWRKDYGTDTILQDFHYDEKPL
IAKFYPQYYHKTDKDGRPVYFEELGAVNLHEMNKVTSEERMLKNLVWEYE
SVVQYRLPACSRAAGHLVETSCTIMDLKGISISSAYSVMSYVREASYISQ
NYYPERMGKFYIINAPFGFSTAFRLFKPFLDPVTVSKIFILGSSYQKELL
KQIPAENLPVKFGGKSEVDGLYLSDIGPWRDPKYIGPEGEAPEA
3D structure
PDB7zg9 Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity.
ChainB
Resolution1.764 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KO0 B Y111 Y122 E124 L147 Y151 S173 T175 M177 Y193 M209 Y109 Y120 E122 L145 Y149 S171 T173 M175 Y191 M207
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008525 phosphatidylcholine transporter activity
GO:0008526 phosphatidylinositol transfer activity
Biological Process
GO:0006896 Golgi to vacuole transport
GO:0015031 protein transport
GO:0015914 phospholipid transport
GO:0030437 ascospore formation
GO:0043001 Golgi to plasma membrane protein transport
GO:0046488 phosphatidylinositol metabolic process
GO:0048194 Golgi vesicle budding
GO:0120009 intermembrane lipid transfer
GO:1901352 negative regulation of phosphatidylglycerol biosynthetic process
GO:2001246 negative regulation of phosphatidylcholine biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7zg9, PDBe:7zg9, PDBj:7zg9
PDBsum7zg9
PubMed36603766
UniProtP24280|SEC14_YEAST SEC14 cytosolic factor (Gene Name=SEC14)

[Back to BioLiP]