Structure of PDB 7zey Chain B

Receptor sequence
>7zeyB (length=64) Species: 9606 (Homo sapiens) [Search protein sequence]
AKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSNL
PESVAYTCVNCTER
3D structure
PDB7zey RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.1.1.364: [histone H3]-lysine(4) N-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C1569 C1572 H1596 C1599 C6 C9 H33 C36
BS02 ZN B C1588 C1591 C1621 C1624 C25 C28 C58 C61
External links
PDB RCSB:7zey, PDBe:7zey, PDBj:7zey
PDBsum7zey
PubMed37075125
UniProtQ03164|KMT2A_HUMAN Histone-lysine N-methyltransferase 2A (Gene Name=KMT2A)

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