Structure of PDB 7z36 Chain B

Receptor sequence
>7z36B (length=446) Species: 9606,10665 [Search protein sequence]
SSSENLYFQGNIFEMLRIDERLRLKIYKDTEGYYTIGIGHLLTKSPSLNA
AKSELDKAIGRNCNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSL
DAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSIWYNQ
TPNRAKRVITTFRTGTWDAYAAEALELLEHCGVCRERLRPEREPRLLPCL
HSACSACLGPGTVVDCPVCKQQCFSKDIVENYFMRDSGSGERTVYCNVHK
HEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRL
GDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVL
VNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLL
SKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWTKSAEAFGKIV
3D structure
PDB7z36 Structure and functional mapping of the KRAB-KAP1 repressor complex.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.2.1.17: lysozyme.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C214 H216 C248 C199 H201 C216
BS02 ZN B C196 C199 C219 C181 C184 C204
BS03 ZN B C278 H281 C301 C246 H249 C269
BS04 ZN B C293 H306 H309 C261 H274 H277
Gene Ontology
Molecular Function
GO:0003796 lysozyme activity
GO:0008270 zinc ion binding
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0016998 cell wall macromolecule catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0044659 viral release from host cell by cytolysis
Cellular Component
GO:0030430 host cell cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7z36, PDBe:7z36, PDBj:7z36
PDBsum7z36
PubMed36341546
UniProtP00720|ENLYS_BPT4 Endolysin (Gene Name=E);
Q13263|TIF1B_HUMAN Transcription intermediary factor 1-beta (Gene Name=TRIM28)

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