Structure of PDB 7z1f Chain B

Receptor sequence
>7z1fB (length=321) Species: 9606 (Homo sapiens) [Search protein sequence]
TTVVATPGQGPDRPQEVSYTDTKIGNGSFGVVYQGELVAIKKVLQNRELQ
IMRKLDHCNIVRLRYFLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLY
MYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGE
PNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDS
GVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPP
EAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFN
FTTQELSSNPPLATILIPPHA
3D structure
PDB7z1f Crystal structure of phosphorylated (Tyr216) GSK3b kinase in complex with CX-4945
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
2.7.11.26: [tau protein] kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3NG B F67 K85 Y134 V135 L188 C199 D200 F29 K41 Y73 V74 L127 C138 D139
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7z1f, PDBe:7z1f, PDBj:7z1f
PDBsum7z1f
PubMed
UniProtP49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta (Gene Name=GSK3B)

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