Structure of PDB 7yxb Chain B

Receptor sequence
>7yxbB (length=192) Species: 9606 (Homo sapiens) [Search protein sequence]
DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVT
ELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTV
YPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRARSE
3D structure
PDB7yxb MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
ChainB
Resolution2.095 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B H13 Y30 Y37 Y47 D57 Y60 W61 L67 T77 Y78 H81 N82 V85 H12 Y29 Y36 Y46 D56 Y59 W60 L66 T76 Y77 H80 N81 V84
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7yxb, PDBe:7yxb, PDBj:7yxb
PDBsum7yxb
PubMed37142807
UniProtA0A1V1IGJ9

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