Structure of PDB 7yx8 Chain B

Receptor sequence
>7yx8B (length=438) Species: 239935 (Akkermansia muciniphila) [Search protein sequence]
GGPDYLYAEYRALPSPRQTGKNLRIGDGFSKYDNMTGVYLEKGRHVVLVG
KTEGQEISLLLPNLMRKPAEGVQPTKDPNGWGLHKKQIPLKEGINIIDVE
TPANAYISYFTEDAGKAPKIPVHFVTGKANGYFDTTRGDTNKDWVRLLDQ
AVSPIMDARGKYIQVAYPVEFLKKFTKDRGTELINAYDKLIGIQYQLMGL
DKYGKIPENRVLARVNFNYYMFRDGDGVAYLGNDGTMRMVTDPENVLKGD
ACWGFSHAVGHVMQMRPMTWGGMTEVSNNIFSLQAAAKTGNESRLKRQGS
YDKARKEIIEGEIAYLQSKDVFNKLVPLWQLHLYFTKNGHPDFYPDVMEY
LRNNAGNYGGNDTVKYQFEFVKACCDVTKTDLTDFFEKWGFFKPGKFHIG
DYAQYDFNVTPEMVEETKKWIAGKGYPKPETDITELSE
3D structure
PDB7yx8 Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut.
ChainB
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B Y287 F290 R291 D292 H325 H329 T342 E343 Y470 Y219 F222 R223 D224 H257 H261 T274 E275 Y402
BS02 peptide B P146 N147 P78 N79
BS03 GAL B E343 Y470 E275 Y402
BS04 ZN B H325 H329 E343 H257 H261 E275
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7yx8, PDBe:7yx8, PDBj:7yx8
PDBsum7yx8
PubMed35882872
UniProtB2UPI7

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