Structure of PDB 7yuj Chain B

Receptor sequence
>7yujB (length=150) Species: 9606 (Homo sapiens) [Search protein sequence]
GPGSSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMN
CKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGC
DWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH
3D structure
PDB7yuj Mechanistic insights into the enzymatic activity of E3 ligase HOIL-1L and its regulation by the linear ubiquitin chain-binding
ChainB
Resolution1.865 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.31: RBR-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C371 C376 C391 C394 C11 C16 C31 C34
BS02 ZN B C399 C402 H406 C411 C39 C42 H46 C51
BS03 ZN B C447 C450 C465 C468 C87 C90 C105 C108
BS04 ZN B C473 C493 C502 C509 C113 C133 C142 C149
BS05 ZN B C495 C506 C509 C135 C146 C149
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:7yuj, PDBe:7yuj, PDBj:7yuj
PDBsum7yuj
PubMed37831767
UniProtQ9BYM8|HOIL1_HUMAN RanBP-type and C3HC4-type zinc finger-containing protein 1 (Gene Name=RBCK1)

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