Structure of PDB 7ysq Chain B

Receptor sequence
>7ysqB (length=426) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
MREIVHIQAGQCGNQIGAKFWEIISDEHGIDATGAYHGDSDLQLERINVY
YNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNN
WAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL
LISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETY
CIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADL
RKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEWIPNNVK
TAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG
EGMDEMEFTEAESNMNDLVSEYQQYQ
3D structure
PDB7ysq Structural insights into the mechanism of GTP initiation of microtubule assembly.
ChainB
Resolution6.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSP B Q11 C12 Q15 N101 G143 T145 Y224 L227 Q11 C12 Q15 N99 G141 T143 Y222 L225
BS02 GTP B L248 K254 L246 K252
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ysq, PDBe:7ysq, PDBj:7ysq
PDBsum7ysq
PubMed37749104
UniProtQ24560|TBB1_DROME Tubulin beta-1 chain (Gene Name=betaTub56D)

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