Structure of PDB 7ykt Chain B

Receptor sequence
>7yktB (length=735) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
FKLPAEFITRPHPSKDHGKETCTAYIHPNVLSSLEINPGSFCTVGKIGEN
GILVIARAGDEEVHPVNVITLSTTIRSVGNLILGDRLELKKAQVQPPYAT
KVTVGSLQGYNILECMEEKVIQKLLDDSGVIMPGMIFQNLKTKAGDESID
VVITDASDDSLPDVSQLDLNMDDMYGGLGSTHITFSKETQANRKYNLPEP
LSYAAVGGLDKEIESLKSAIEIPLHQPTLFSSFGVSPPRGILLHGPPGTG
KTMLLRVVANTSNAHVLTINGPSIVSKYLGETEAALRDIFNEARKYQPSI
IFIDEIDSIAPNRANDDSGEVESRVVATLLTLMDGMGAAGKVVVIAATNR
PNSVDPALRRPGRFDQEVEIGIPDVDARFDILTKQFSRMSSDRHVLDSEA
IKYIASKTHGYVGADLTALCRESVMKTIQRGLGTDANIDKFSLKVTLKDV
ESAMVDIRPSAMREIFLEMPKVYWSDIGGQEELKTKMKEMIQLPLEASET
FARLGISAPKGVLLYGPPGCSKTLTAKALATESGINFLAVKGPEIFNKYV
GESERAIREIFRKARSAAPSIIFFDEIDALSPDRDGSSTSAANHVLTSLL
NEIDGVEELKGVVIVAATNRPDEIDAALLRPGRLDRHIYVGPPDVNARLE
ILKKCTKKFNTEESGVDLHELADRTEGYSGAEVVLLCQEAGLAAIMEDLD
VAKVELRHFEKAFKGIARGITPEMLSYYEEFALRS
3D structure
PDB7ykt Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition.
ChainB
Resolution5.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.10: non-chaperonin molecular chaperone ATPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP B G289 G291 T293 M294 I422 G454 A455 T458 G248 G250 T252 M253 I381 G413 A414 T417
BS02 ADP B P559 G560 C561 K563 T564 L565 E617 N660 V725 P518 G519 C520 K522 T523 L524 E576 N619 V684
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009410 response to xenobiotic stimulus
GO:0034214 protein hexamerization
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7ykt, PDBe:7ykt, PDBj:7ykt
PDBsum7ykt
PubMed36351914
UniProtP32794|AFG2_YEAST ATPase family gene 2 protein (Gene Name=AFG2)

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