Structure of PDB 7y5g Chain B

Receptor sequence
>7y5gB (length=302) Species: 8364 (Xenopus tropicalis) [Search protein sequence]
HCHNNNKKAYDARQREQTFAKKKLCIASLICFVFISAEIVGGYIAGSLAH
LLVDLSSFFISLCSLWLSSKSSTTRLTFGWHRAEILGALMSVITIWLVTG
VLVYLACERLIRPDYTIDGTVMLITSACALGANLVLALILHYKPQTNASI
RAAFIHVIGDLFQSISVLISALIIYFKPEYKMADPICTFIFSIFVLITTV
TVLRDLLTVLMEGTPRGIHYSDVKQSILAVDGVKSVHSLHLWALTMNQVI
LSAHIATDIVGESKRILKDVTQNVFARFPFHSVTIQVEPIEDQSPECMFC
YE
3D structure
PDB7y5g Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism.
ChainB
Resolution3.85 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H306 H323 E357 H237 H254 E288
BS02 ZN B H100 H225 D229 H50 H156 D160
BS03 ZN B H45 H47 H1 H3
Gene Ontology
Molecular Function
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015297 antiporter activity
GO:0046872 metal ion binding
GO:0140826 zinc:proton antiporter activity
Biological Process
GO:0006812 monoatomic cation transport
GO:0006829 zinc ion transport
GO:0055085 transmembrane transport
GO:0062111 zinc ion import into organelle
GO:0071577 zinc ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030658 transport vesicle membrane
GO:0030667 secretory granule membrane
GO:0031410 cytoplasmic vesicle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7y5g, PDBe:7y5g, PDBj:7y5g
PDBsum7y5g
PubMed36464198
UniProtQ5XHB4|ZNT8_XENTR Proton-coupled zinc antiporter SLC30A8 (Gene Name=slc30a8)

[Back to BioLiP]