Structure of PDB 7y0e Chain B

Receptor sequence
>7y0eB (length=131) Species: 9606 (Homo sapiens) [Search protein sequence]
CSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYS
SQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVSTSFMKLNTSA
GNVDIYKKLYHSCSSKAVVSLRCIACGVNLN
3D structure
PDB7y0e Crystal structure of TMPRSS2 in complex with Camostat
ChainB
Resolution2.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.122: transmembrane protease serine 2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B N131 D134 V136 H138 D144 E145 N19 D22 V24 H26 D32 E33
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:7y0e, PDBe:7y0e, PDBj:7y0e
PDBsum7y0e
PubMed37990007
UniProtO15393|TMPS2_HUMAN Transmembrane protease serine 2 (Gene Name=TMPRSS2)

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