Structure of PDB 7xwo Chain B

Receptor sequence
>7xwoB (length=272) Species: 562,9606 [Search protein sequence]
SMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLA
LADLCMAAFNAAFNFVYASHWYFGRAFCYFQNLFPITAMFVSIYSMTAIA
ADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGA
TKCVVAWPGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRNLRHL
QAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLAL
FWLAMSSTMYNPIIYCCLNHRF
3D structure
PDB7xwo Neurokinin A bound to active human neurokinin 2 receptor in complex with G324
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B N86 Y93 T173 D175 C181 Y266 Y269 F270 Q286 Y289 F293 N60 Y67 T145 D147 C153 Y224 Y227 F228 Q244 Y247 F251
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004995 tachykinin receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0042597 periplasmic space

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Molecular Function

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Cellular Component
External links
PDB RCSB:7xwo, PDBe:7xwo, PDBj:7xwo
PDBsum7xwo
PubMed35882833
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P21452

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