Structure of PDB 7xvz Chain B

Receptor sequence
>7xvzB (length=224) Species: 9606 (Homo sapiens) [Search protein sequence]
LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISW
AKKIPGFVELSLFDQVRLLESSWMEVLMMGLMWRSIDHPGKLIFAPDLVL
DRDEGKSVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSDSS
RKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGM
EHLLNMKSKNVVPVYDLLLEMLNA
3D structure
PDB7xvz Evaluating the correlation of binding affinities between isothermal titration calorimetry and fragment molecular orbital method of estrogen receptor beta with diarylpropionitrile (DPN) or DPN derivatives.
ChainB
Resolution2.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B K314 E493 K52 E220
BS02 I1D B M295 L298 E305 M336 L339 F356 H475 L476 M33 L36 E43 M74 L77 F94 H202 L203
External links
PDB RCSB:7xvz, PDBe:7xvz, PDBj:7xvz
PDBsum7xvz
PubMed35810932
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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