Structure of PDB 7xvw Chain B

Receptor sequence
>7xvwB (length=389) Species: 2116483 (Wuhan spiny eel influenza virus) [Search protein sequence]
EWRFPKSTCPGRSLQKMLQLNPHRHATAGSQAATIPNREPFISCSQDECR
LFTLDHDVSTPGAYDGITWEDRSKRRRLVSFPLGSELTLDNMKVHLSGWS
GTACHDGKEWTYATVNGPDNSAVMRLKYGDQIRGSFPSYANNILRTQESE
CVCIDGKCYIIVIDGPAGGTATPKVLVTREGEVTSEIIVTGRNKMGEECS
CLATNRTWIECLCRDNAFSAKRPIIRIDTVAGTARGYLMCSDTYLDTPRP
ADGSITGSCETDGTSGGGGVKGAFALSRTTEATTERFYVRTVSSSARSGA
VFYKTTDDPTESNNPLTLIGTAVGGAIPMWYSFSFEIPGKVCDQTCIGLE
MGLTMGHQLWTSNSVAVYCVIGDNLDWDSTTDVVPADIV
3D structure
PDB7xvw Structure of neuraminidase from influenza B-like viruses derived from spiny eel
ChainB
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BCZ B R121 E122 D154 R155 W182 R228 E231 E280 R297 R380 Y414 R38 E39 D71 R72 W99 R145 E148 E197 R214 R297 Y331
BS02 CA B D298 S302 D329 G349 G351 D215 S219 D246 G266 G268
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7xvw, PDBe:7xvw, PDBj:7xvw
PDBsum7xvw
PubMed36191180
UniProtA0A2P1GNP4

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