Structure of PDB 7xve Chain B

Receptor sequence
>7xveB (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
GCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVK
ILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDY
ECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVV
LTIWLVAEMIYCYKKIAAATETA
3D structure
PDB7xve Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Na v 1.7.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LPE B W173 E177 C181 W154 E158 C162
BS02 LPE B V175 Y182 V156 Y163
Gene Ontology
Molecular Function
GO:0017080 sodium channel regulator activity
Biological Process
GO:0006814 sodium ion transport
Cellular Component
GO:0001518 voltage-gated sodium channel complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xve, PDBe:7xve, PDBj:7xve
PDBsum7xve
PubMed35878056
UniProtQ07699|SCN1B_HUMAN Sodium channel subunit beta-1 (Gene Name=SCN1B)

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