Structure of PDB 7xu8 Chain B

Receptor sequence
>7xu8B (length=166) Species: 9838 (Camelus dromedarius) [Search protein sequence]
CGSIVPRREWRALASECRERLTRPVRYVVVSHTAGSHCDTPASCAQQAQN
VQSYHVRNLGWCDVGYNFLIGEDGLVYEGRGWNIKGAHAGPTWNPISIGI
SFMGNYMNRVPPPRALRAAQNLLACGVALGALRSNYEVKGHRDVQPTLSP
GDRLYEIIQTWSHYRA
3D structure
PDB7xu8 Ligand recognition by peptidoglycan recognition protein-S (PGRP-S): structure of the complex of camel PGRP-S with heptanoic acid at 2.15 angstrom resolution.
ChainB
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PEO B W66 C67 R85 W61 C62 R80
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
GO:0016019 peptidoglycan immune receptor activity
GO:0042834 peptidoglycan binding
Biological Process
GO:0001818 negative regulation of cytokine production
GO:0009253 peptidoglycan catabolic process
GO:0016045 detection of bacterium
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region

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Cellular Component
External links
PDB RCSB:7xu8, PDBe:7xu8, PDBj:7xu8
PDBsum7xu8
PubMed36188729
UniProtQ9GK12|PGRP1_CAMDR Peptidoglycan recognition protein 1 (Gene Name=PGLYRP1)

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