Structure of PDB 7xu5 Chain B

Receptor sequence
>7xu5B (length=938) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search protein sequence]
AYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAINPVLPFND
GVYFASTEKSNIIRGWIFGSLLIVNNATNVVIKVCEFQSEFRVYSFEYVS
QPKNLREFVFKNIDGYFKIYSKHTPILPQGFSALEPLVDLPIITRFQTLL
ALAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEK
GIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISN
CVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQI
APGQTGKIADYNYKLPCDFTGCVIAWNSNNLNYNYLYRLFRKSNLKPFER
DPLQSYGFQPGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNF
NGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFG
GVSVITPGTNTSNQVAVLYQGVNCTEVNVFQTRAGCLIGAEHVNNSYECD
IPIGAGICASYQTSQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTE
ILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQD
KNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNK
VTFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQM
AYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVV
NQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKCEAEVQIDRLITGRLQ
SLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSF
PQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHW
FVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDP
3D structure
PDB7xu5 Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BLA B N99 R102 N121 A123 R190 F192 H207 L226 N61 R64 N75 A77 R106 F108 H123 L137
Gene Ontology
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046813 receptor-mediated virion attachment to host cell
GO:0075509 endocytosis involved in viral entry into host cell
Cellular Component
GO:0016020 membrane
GO:0019031 viral envelope
GO:0055036 virion membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7xu5, PDBe:7xu5, PDBj:7xu5
PDBsum7xu5
PubMed35905112
UniProtP0DTC2|SPIKE_SARS2 Spike glycoprotein (Gene Name=S)

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