Structure of PDB 7xty Chain B

Receptor sequence
>7xtyB (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
KPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGR
IHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKG
3D structure
PDB7xty Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S1377 L1378 G1379 I1380 S1381 V1382 T1383 S1389 V1390 I1401 H1431 V1435 R1439 S16 L17 G18 I19 S20 V21 T22 S28 V29 I40 H70 V74 R78
External links
PDB RCSB:7xty, PDBe:7xty, PDBj:7xty
PDBsum7xty
PubMed
UniProtQ12923|PTN13_HUMAN Tyrosine-protein phosphatase non-receptor type 13 (Gene Name=PTPN13)

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