Structure of PDB 7xs6 Chain B

Receptor sequence
>7xs6B (length=729) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
FKLWNGNFVFDSPISKTLLDQYATTTENANTLPNEFKFMRYQAVTCEPNQ
LAEKNFTVRQLKYLTPRETELMLVVTMYNEDHILLGRTLKGIMDNVKYMV
KKKNSSTWGPDAWKKIVVCIISDGRSKINERSLALLSSLGCYQDGFAKDE
INEKKVAMHVYEHTTMINITNISESEVSLECNQGTVPIQLLFCLKEQNQK
KINSHRWAFEGFAELLRPNIVTLLDAGTMPGKDSIYQLWREFRNPNVGGA
CGEIRTDLGKRFVKLLNPLVASQNFEYKMSNILDKTTESNFGFITVLPGA
FSAYRFEAVRGQPLQKYFYGEGFHFFSSNMYLAEDRILCFEVVTKKNCNW
ILKYCRSSYASTDVPERVPEFILQRRRWLNGSFFASVYSFCHFYRVWSSG
HNIGRKLLLTVEFFYLFFNTLISWFSLSSFFLVFRILTVSIALAYHSAFN
VLSVIFLWLYGICTLSTFILSLGNKPKSTEKFYVLTCVIFAVMMIYMIFC
SIFMSVKSFQNILKTEAFRDIVISLGSTYCLYLISSIIYLQPWHMLTSFI
QYILLSPSYINVLNIYAFCNVHDLSWGTKGAMANPLGKINTTEDGTFKME
VLVSSSEIQANYDKYLKVLNDFDPKSESRPTEPSYDEKKTGYYANVRSLV
IIFWVITNFIIVAVVLETGGIADYIAMKSISTAEIPLMTSKASIYFNVIL
WLVALSALIRFIGCSIYMIVRFFKKVTFR
3D structure
PDB7xs6 structure of a membrane-integrated glycosyltransferase with inhibitor
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.16: chitin synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGI B T453 Y455 E457 D500 K578 D602 P675 T744 D745 W760 T76 Y78 E80 D123 K201 D225 P298 T362 D363 W378
BS02 0V9 B F813 L839 W840 L847 F850 V1048 L1059 T1061 F431 L457 W458 L465 F468 V655 L666 T668
BS03 0V9 B F1052 T1061 G1062 D1066 F659 T668 G669 D673
Gene Ontology
Molecular Function
GO:0004100 chitin synthase activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0000920 septum digestion after cytokinesis
GO:0006031 chitin biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0030428 cell septum
GO:0045009 chitosome
GO:0071944 cell periphery

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xs6, PDBe:7xs6, PDBj:7xs6
PDBsum7xs6
PubMed
UniProtP08004|CHS1_YEAST Chitin synthase 1 (Gene Name=CHS1)

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