Structure of PDB 7xn5 Chain B

Receptor sequence
>7xn5B (length=422) Species: 536 (Chromobacterium violaceum) [Search protein sequence]
AAAAGKIGAFLRKAVAAQSYGLMFANGKLFEATGDALEKRGQYGFSALQR
LDGLSRRNLAAVEARLGALDSAERGLKERIMTGAWHFRHQSNAALDDGKT
AAIASNHLLARESRSSGGNTFAGDKALLSNHDFVFFGVEFSGRGKQDKPL
NHKHSTMDFGANAYVVPDTLPACRHGYLTLTDHFFNRVPGGREAEHQDFV
GSFPQMGAETGRWIHEGKYRQNAPIFNYRDMKAAVALHLIEFLRDSKDAA
FKAYVFDQAMQSGQALDRVLNSVFQAEFHIPRLMATTDYAKHPLRPMLLK
EAVDSVNLPALSGLVSSKGDAVTAMWHAIDKGKDAVAAHLLGNWRFEAGD
FASAPPGFYHELNYALSEHGASVYILDQFLSRGWAAVNAPFEHVNSGETM
LDNAVKYGNREMAAALIKHGAD
3D structure
PDB7xn5 Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin.
ChainB
Resolution3.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.3.99.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NCA B H137 F183 F184 H202 F207 E325 H89 F135 F136 H154 F159 E277
BS02 APR B S139 A141 L143 A152 N154 G166 N167 F183 F207 S91 A93 L95 A104 N106 G118 N119 F135 F159
Gene Ontology
Molecular Function
GO:0005516 calmodulin binding
GO:0016829 lyase activity
GO:0090729 toxin activity
GO:0140740 ADP-riboxanase activity
Biological Process
GO:0052040 symbiont-mediated perturbation of host programmed cell death
Cellular Component
GO:0005576 extracellular region
GO:0030430 host cell cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xn5, PDBe:7xn5, PDBj:7xn5
PDBsum7xn5
PubMed36423631
UniProtQ7NWF2|COPC_CHRVO Arginine ADP-riboxanase CopC (Gene Name=copC)

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