Structure of PDB 7xm0 Chain B

Receptor sequence

>7xm0B (length=254) Species: 1280 (Staphylococcus aureus) [Search protein sequence]

SIEDIVFEKFQPYINWSIDKLCEHFSINKGEKGLNYRIASAILNLKGKTT
KSKPFPEVEEFEKSSIVVKTVHFNKKNVNKESMSFGAFKFEELANEEWED
SEGYPSAQWRNFLLETRFLFFVVKEDEDGVDIFKGIKFFSMPEEDINGPV
KRMWDDTVKKLKEGVTLEAVPDKSTKDGWRIKNNFVDKSDDLICHVRPHT
NNRDYRGGSNADKLPKKINWINRPDSDDYSDEWMTKQSFWINNDYIKKQV
EDLL

3D structure

PDB

7xm0 The Self-Activation Mechanism of Type IIE Restriction Endonuclease Sau3AI

Chain

Resolution

2.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

3.1.21.4: type II site-specific deoxyribonuclease.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	B	K267 Y271 K304 T305 K315 E316 S319 H434 N436 S444 K471 W475	K32 Y36 K69 T70 K80 E81 S84 H199 N201 S209 K236 W240
BS02	dna	B	E266 K267 R272 R415 I416 K417 N418 D422 K423 S424 R432 P433 T435 N436 N437 R438 Y440	E31 K32 R37 R180 I181 K182 N183 D187 K188 S189 R197 P198 T200 N201 N202 R203 Y205
BS03	MG	B	N418 F420 D422	N183 F185 D187

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity

View graph for
Molecular Function

External links

PDB	RCSB:7xm0, PDBe:7xm0, PDBj:7xm0
PDBsum	7xm0
PubMed
UniProt	P16667\|T2S3_STAAU Type II restriction enzyme Sau3AI (Gene Name=sau3AIR)

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