Structure of PDB 7xey Chain B

Receptor sequence
>7xeyB (length=519) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
CRFETSELQASVMISTPLFTDSWSSCNTANCNGSIKIHDIAGITYVAIPA
VSMIQLGNLVGLPVTGDVLFPGLSSDEPLPMVDAAILKLFLQLKIKEGLE
LELLGKKLVVITGHSTGGALAAFTALWLLSQSSPPSFRVFCITFGSPLLG
NQSLSTSISRSRLAHNFCHVVSIHDLVPRSSNEQFWPFGTYLFCSDKGGV
CLDNAGSVRLMFNILNTTATQNTEEHQRYGHYVFTLSHMFLKSRSFLGGS
IPDNSYQAGVALAVEALGFSNDDTSGVLVKECIETATRIVRAPILRSAEL
ANELASVLPARLEIQWYKDRCDASEEQLGYYDFFKRYSLKRDFKVNMSRI
RLAKFWDTVIKMVETNELPFDFHLGKKWIYASQFYQLLAEPLDIANFYKN
RDIGGHYLEGNRPKRYEVIDKWQKGVKVPEECVRSRYASTTQDTCFWAKL
EQAKEWLDEARKESSDPQRRSLLREKIVPFESYANTLVTKKEVSLDVKAK
NSSYSVWEANLKEFKCKMG
3D structure
PDB7xey Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity.
ChainB
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP B K379 K380 Y383 K376 K377 Y380
BS02 RP5 B R314 F387 R311 F384
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016298 lipase activity
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0001666 response to hypoxia
GO:0002213 defense response to insect
GO:0006629 lipid metabolic process
GO:0009617 response to bacterium
GO:0009625 response to insect
GO:0009626 plant-type hypersensitive response
GO:0009627 systemic acquired resistance
GO:0009751 response to salicylic acid
GO:0009862 systemic acquired resistance, salicylic acid mediated signaling pathway
GO:0009873 ethylene-activated signaling pathway
GO:0010105 negative regulation of ethylene-activated signaling pathway
GO:0010150 leaf senescence
GO:0010225 response to UV-C
GO:0010310 regulation of hydrogen peroxide metabolic process
GO:0010618 aerenchyma formation
GO:0016042 lipid catabolic process
GO:0031348 negative regulation of defense response
GO:0042742 defense response to bacterium
GO:0050829 defense response to Gram-negative bacterium
GO:0051707 response to other organism
GO:0060866 leaf abscission
GO:0071327 cellular response to trehalose stimulus
GO:0080142 regulation of salicylic acid biosynthetic process
GO:0080151 positive regulation of salicylic acid mediated signaling pathway
GO:1900367 positive regulation of defense response to insect
GO:1900426 positive regulation of defense response to bacterium
GO:1901183 positive regulation of camalexin biosynthetic process
GO:2000022 regulation of jasmonic acid mediated signaling pathway
GO:2000031 regulation of salicylic acid mediated signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0106093 EDS1 disease-resistance complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7xey, PDBe:7xey, PDBj:7xey
PDBsum7xey
PubMed35857645
UniProtQ9S745|PAD4_ARATH Lipase-like PAD4 (Gene Name=PAD4)

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