Structure of PDB 7xct Chain B

Receptor sequence
>7xctB (length=83) Species: 9606 (Homo sapiens) [Search protein sequence]
KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDA
VTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
3D structure
PDB7xct H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
ChainB
Resolution2.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R35 R45 I46 G48 K79 T80 R16 R26 I27 G29 K60 T61
BS02 dna B P32 R36 R45 P13 R17 R26
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:7xct, PDBe:7xct, PDBj:7xct
PDBsum7xct
PubMed35739357
UniProtP62805|H4_HUMAN Histone H4 (Gene Name=H4C1)

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