Structure of PDB 7xbz Chain B

Receptor sequence
>7xbzB (length=187) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
LIPTVIETGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQD
SEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLA
AGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILS
ERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVP
3D structure
PDB7xbz Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP.
ChainB
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.92: endopeptidase Clp.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 D4E B L24 I29 Y61 Y63 I91 I93 M190 L19 I24 Y56 Y58 I86 I88 M185
BS02 MG B I81 P86 I76 P81
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0051117 ATPase binding
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
Cellular Component
GO:0005737 cytoplasm
GO:0009368 endopeptidase Clp complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7xbz, PDBe:7xbz, PDBj:7xbz
PDBsum7xbz
PubMed36376309
UniProtQ2G036|CLPP_STAA8 ATP-dependent Clp protease proteolytic subunit (Gene Name=clpP)

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