Structure of PDB 7x5g Chain B

Receptor sequence
>7x5gB (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
LTRDELRAKALHIPFPVEKIINLPVVDFNEMMSKEQFNEAQLALIRDIRR
RGKNKVYAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLL
KKQLS
3D structure
PDB7x5g Structural basis of transcription regulation by CNC family transcription factor, Nrf2.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B R504 N507 K508 R515 R51 N54 K55 R62
BS02 dna B R499 R502 N507 Y510 C514 K518 R46 R49 N54 Y57 C61 K65
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function

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Biological Process
External links
PDB RCSB:7x5g, PDBe:7x5g, PDBj:7x5g
PDBsum7x5g
PubMed36454022
UniProtQ16236|NF2L2_HUMAN Nuclear factor erythroid 2-related factor 2 (Gene Name=NFE2L2)

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