Structure of PDB 7x1z Chain B

Receptor sequence

>7x1zB (length=484) Species: 32046 (Synechococcus elongatus) [Search protein sequence]

EHQAIAKMRTMIEGFDDISHGGLPIGRSTLVSGTSGTGKTLFSIQFLYNG
IIEFDEPGVFVTFEETPQDIIKNARSFGWDLAKLVDEGKLFILDASPDPE
GQEVVGGFDLSALIERINYAIQKYRARRVSIDSVTSVFQQYDASSVVRRE
LFRLVARLKQIGATTVMTTERIEEYGPIARYGVEEFVSDNVVILRNVLEG
ERRRRTLEILKLRGTSHMKGEYPFTITDHGINIFPLGAMRLTQRSSNVRV
SSGVVRLDEMCGGGFFKDSIILATGATGTGKTLLVSRFVENACANKERAI
LFAYEESRAQLLRNAYSWGMDFEEMERQNLLKIVCAYPESAGLEDHLQII
KSEINDFKPARIAIDSLSALARGVSNNAFRQFVIGVTGYAKQEEITGLFT
NTSDQFMGAHSITDSHIEEITDTIILLQYVEIRGEMSRAINVFKMRGSWH
DKAIREFMISDKGPDIKDSFRNFERIISGSPTRI

3D structure

PDB

7x1z A cooperative switch within the KaiC hexamer revealed by cryo-EM

Chain

Resolution

3.3 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

2.7.11.1: non-specific serine/threonine protein kinase.
3.6.4.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	ATP	B	E432 M458 S461 H463	E419 M445 S448 H450
BS02	ATP	B	K224 R226 T228 S229 H230	K211 R213 T215 S216 H217
BS03	ATP	B	G291 T292 G293 K294 T295 S330 W331 R451	G278 T279 G280 K281 T282 S317 W318 R438
BS04	ATP	B	G49 T50 G51 K52 T53 L54 F90 I239	G36 T37 G38 K39 T40 L41 F77 I226
BS05	MG	B	T295 E318 D378	T282 E305 D365

Gene Ontology

	Molecular Function
GO:0000287	magnesium ion binding
GO:0003677	DNA binding
GO:0004674	protein serine/threonine kinase activity
GO:0004712	protein serine/threonine/tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016787	hydrolase activity
GO:0016887	ATP hydrolysis activity
GO:0042802	identical protein binding
GO:0044024	histone H2AS1 kinase activity
GO:0046872	metal ion binding
GO:0106310	protein serine kinase activity

	Biological Process
GO:0006338	chromatin remodeling
GO:0006355	regulation of DNA-templated transcription
GO:0007623	circadian rhythm
GO:0009649	entrainment of circadian clock
GO:0016310	phosphorylation
GO:0042752	regulation of circadian rhythm
GO:0042754	negative regulation of circadian rhythm
GO:0048511	rhythmic process
GO:0070297	regulation of phosphorelay signal transduction system

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:7x1z, PDBe:7x1z, PDBj:7x1z
PDBsum	7x1z
PubMed
UniProt	Q79PF4\|KAIC_SYNE7 Circadian clock oscillator protein KaiC (Gene Name=kaiC)

[Back to BioLiP]