Structure of PDB 7wn6 Chain B

Receptor sequence
>7wn6B (length=711) Species: 9606 (Homo sapiens) [Search protein sequence]
SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNG
KRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKL
SGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGT
LTSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLK
STSVFARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEG
MVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGC
SCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWIC
SNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIET
VQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD
LRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNG
NQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRF
SEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASY
AAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEEC
NEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMC
YCEDGFMHCTM
3D structure
PDB7wn6 Structural mechanism of VWF D'D3 dimer formation.
ChainB
Resolution3.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA B D47 N164 N166 F168 D172 D18 N135 N137 F139 D143
BS02 CA B D400 N526 N528 D533 D534 D371 N497 N499 D504 D505
External links
PDB RCSB:7wn6, PDBe:7wn6, PDBj:7wn6
PDBsum7wn6
PubMed35169124
UniProtP04275|VWF_HUMAN von Willebrand factor (Gene Name=VWF)

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