Structure of PDB 7wku Chain B

Receptor sequence
>7wkuB (length=299) Species: 1586324 (Porcine deltacoronavirus) [Search protein sequence]
SAGIKILLHPSGVVERCMVSVVYNGSALNGIWLKNVVYCPRHVIGKFRGD
QWTHMVSIADCRDFIVKCPIQGIQLNVQSVKMVGALLQLTVHTNNTATPD
YKFERLQPGSSMTIACAYDGIVRHVYHVVLQLNNLIYASFLNGACGSVGY
TLKGKTLYLHYMHHIEFNNKTHSGTDLEGNFYGPYVDEEVIQQQTAFQYY
TDNVVAQLYAHLLTVDARPKWLAQSQISIEDFNSWAANNSFANFPCEQTN
MSYIMGLSQTARVPVERILNTIIQLTTNRDSYDFECDWTPEMVYNQAPI
3D structure
PDB7wku The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
3.4.19.12: ubiquitinyl hydrolase 1.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B H41 K45 F139 G142 C144 H162 H163 I164 E165 F166 E188 H42 K46 F140 G143 C145 H163 H164 I165 E166 F167 E189
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0019082 viral protein processing

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7wku, PDBe:7wku, PDBj:7wku
PDBsum7wku
PubMed35336895
UniProtA0A140ESF0

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