Structure of PDB 7wgl Chain B

Receptor sequence
>7wglB (length=256) Species: 9606 (Homo sapiens) [Search protein sequence]
ADLKAFSKHIYNAYLKNFNMTKKKARSILTGAPFVIHDIETLWQAEKGLV
WLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLK
YGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFE
FAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEF
HLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLL
QEIYKD
3D structure
PDB7wgl Functional and Structural Insights into Human PPAR alpha / delta / gamma Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate.
ChainB
Resolution2.091 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PEM B F246 C249 Q250 T252 T253 H287 L303 V305 I327 I328 H413 L433 Y437 F63 C66 Q67 T69 T70 H104 L120 V122 I144 I145 H230 L250 Y254
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7wgl, PDBe:7wgl, PDBj:7wgl
PDBsum7wgl
PubMed35563117
UniProtQ03181|PPARD_HUMAN Peroxisome proliferator-activated receptor delta (Gene Name=PPARD)

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