Structure of PDB 7wf3 Chain B

Receptor sequence
>7wf3B (length=252) Species: 9606 (Homo sapiens) [Search protein sequence]
ERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLP
EFRSSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVA
IIPYFITLGTELAERQGSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTL
KASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVT
MTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRET
EG
3D structure
PDB7wf3 Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug.
ChainB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K B G446 G448 G205 G207
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005249 voltage-gated potassium channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006813 potassium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7wf3, PDBe:7wf3, PDBj:7wf3
PDBsum7wf3
PubMed35091471
UniProtP22001|KCNA3_HUMAN Potassium voltage-gated channel subfamily A member 3 (Gene Name=KCNA3)

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