Structure of PDB 7w9p Chain B

Receptor sequence
>7w9pB (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
GCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVK
ILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDY
ECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVV
LTIWLVAEMIYCYKKIAAATETA
3D structure
PDB7w9p High-resolution structures of human Na v 1.7 reveal gating modulation through alpha-pi helical transition of S6 IV.
ChainB
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LPE B M178 I179 M159 I160
Gene Ontology
Molecular Function
GO:0017080 sodium channel regulator activity
Biological Process
GO:0006814 sodium ion transport
Cellular Component
GO:0001518 voltage-gated sodium channel complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7w9p, PDBe:7w9p, PDBj:7w9p
PDBsum7w9p
PubMed35476982
UniProtQ07699|SCN1B_HUMAN Sodium channel subunit beta-1 (Gene Name=SCN1B)

[Back to BioLiP]