Structure of PDB 7w6m Chain B

Receptor sequence
>7w6mB (length=1224) Species: 28295 (Porcine epidemic diarrhea virus) [Search protein sequence]
NFRRFFSKFNVQAPAVVVLGGYLPIGENQGVNSTWYCAGQHPTASGVHGI
FVSHIRGGHGFEIGISQEPFDPSGYQLYLHKATNGNTNATARLRICQFPS
IKTLGPTANNDVTIGRNCLFNKAIPAHMSEHSVVGITWDNDRVTVFSDKI
YYFYFKNDWSRVATKCYNSGGCAMQYVYEPTYYMLNVTSAGEDGISYQPC
TANCIGYAANVFATEPNGHIPEGFSFNNWFLLSNDSTLVHGKVVSNQPLL
VNCLLAIPKIYGLGQFFSFNQTIDGVCNGAAVQRAPEALRFNINDTSVIL
AEGSIVLHTALGTNFSFVCSNSSNPHLATFAIPLGATQVPYYCFFKVDTY
NSTVYKFLAVLPPTVREIVITKYGDVYVNGFGYLHLGLLDAVTINFTGHG
TDDDVSGFWTIASTNFVDALIEVQGTAIQRILYCDDPVSQLKCSQVAFDL
DDGFYPFSSRNLLSHEQPISFVTLPSFNAHSFVNITVSASFGGHSGANLI
ASDTTINGFSSFCVDTRQFTISLSYNVTNSYGYVSNSQDSNCPFTLQSVN
DYLSFSKFCVSTSLLASACTIDLFGYPEFGSGVKFTSLYFQFTKGELITG
TPKPLEGVTDVSFMTLDVCTKYTIYGFKGEGIITLTNSSFLAGVYYTSDS
GQLLAFKNVTSGAVYSVTPCSFSEQAAYVDDDIVGVISSLSSSTFNSTRE
LPGFFYHSNDGSNCTEPVLVYSNIGVCKSGSIGYVPSQSGQVKIAPTVTG
NISIPTNFSMSIRTEYLQLYNTPVSVDCATYVCNGNSRCKQLLTQYTAAC
KTIESALQLSARLESVEVNSMLTISEEALQLATISSFNGDGYNFTNVLGV
SVYDPARGRVVQKRSFIEDLLFNKVVTNGLGTVDEDYKRCSNGRSVADLV
CAQYYSGVMVLPGVVDAEKLHMYSASLIGGMVLGGFTAAAALPFSYAVQA
RLNYLALQTDVLQRNQQLLAESFNSAIGNITSAFESVKEASSQTSRGLNT
VAHALTKVQEVVNSQGAALTQLTVQLQHNFQAISSSIDDIYSRLDILSAD
VQVDRLITGRLSALNAFVAQTLTKYTEVQASRKLAQQKVNECVKSQSQRY
GFCGGDGEHIFSLVQAAPQGLLFLHTVLVPSDFVDVIAIAGLCVNDEIAL
TLREPGLVLFTHELQNHTATEYFVSSRRMFEPRKPTVSDFVQIESCVVTY
VNLTRDQLPDVIPDYIDVNKTRDE
3D structure
PDB7w6m In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM.
ChainB
Resolution4.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BMA B A138 N139 A108 N109
Gene Ontology
Biological Process
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0046813 receptor-mediated virion attachment to host cell
GO:0075509 endocytosis involved in viral entry into host cell
Cellular Component
GO:0016020 membrane
GO:0019031 viral envelope
GO:0033644 host cell membrane
GO:0044173 host cell endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0055036 virion membrane

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7w6m, PDBe:7w6m, PDBj:7w6m
PDBsum7w6m
PubMed35986008
UniProtA0A1Y0DD46

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