Structure of PDB 7vzz Chain B

Receptor sequence

>7vzzB (length=677) Species: 1912 (Streptomyces hygroscopicus)

MLVLGLNGNFSAADTDVVPQLGEVFFHDSAASLIRDGELVAAVEEERLNR
IKKTTKFPLNAVRECLALAGARPEDVDAVGYYFPENHIDTVLNHLYTEYP
RAPLRYSRELIRQRLKEGLGWDLPDEKLVYVPHHEAHAYSSYLHSGMDSA
LVLVLDGRGELHSGTVYRAEGTRLEKLADYPVPKSLGGLYLNATYLLGYG
FGDEYKVMGLAPWGNPETYRDTFAKLYTLQDNGEYELHGNIMVPNLVSPL
FYAEGFRPRRKGEPFTQAHRDFAAALQETVEKIVLHILEYWAKTSGHSRL
CFGGGVAHNSSLNGLILKSGLFDEVFVHPASHDAGAGEGAAYAAAASLGT
LERPGKRLLSASLGPALGGREQIRARLADWAPLIDVEFPDDAVETAAGLL
AEGQVLGWAYGRSEFGPRALGHRSIVADARPEENRTRINAMVKKREGFRP
FAPVVTAEAARDYFDLSGADGNHEFMSFVVPVLPERRTELGAVTHVDGTA
RVQVVSAESGERFHRLVRRFGELTGTPVLLNTSFNNNAEPIVQSLDDVVT
SFLTTDLDVLVVEDCLVRGKASPDLGVLVPRFRPVTRLVERRTAGPDASA
GAKTHEIHLDYDGGPSAKVSPELYELLGAVDGTTTLGDLAKTVGGLSDAL
ATEVFALWEQRFLTLAPAGDIGPLADD

3D structure

• PDB: 7vzz Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
• Chain: B
• Resolution: 2.85 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	8CW	B	M242 V243 P244	M242 V243 P244
BS02	FE	B	H133 H137 D156 D333	H133 H137 D156 D333
BS03	CA0	B	H137 G157 G187 Y190 E204 G305 N309 H332 D333	H137 G157 G187 Y190 E204 G305 N309 H332 D333
BS04	83Z	B	V24 F25 F26 H27 H87 G157 R158	V24 F25 F26 H27 H87 G157 R158

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0005524 ATP binding
• GO:0046872 metal ion binding

Biological Process

• GO:0009058 biosynthetic process

External links

• PDB: RCSB:7vzz, PDBe:7vzz, PDBj:7vzz
• PDBsum: 7vzz
• PubMed: 36329057
• UniProt: Q84G19