Structure of PDB 7vyp Chain B

Receptor sequence

>7vypB (length=674) Species: 1912 (Streptomyces hygroscopicus)

MLVLGLNGNFSAADTDVVPQLGEVFFHDSAASLIRDGELVAAVEEERLNR
IKKTTKFPLNAVRECLALAGARPEDVDAVGYYFPENHIDTVLNHLYTEYP
RAPLRYSRELIRQRLKEGLGWDLPDEKLVYVPHHEAHAYSSYLHSGMDSA
LVLVLDGRGELHSGTVYRAEGTRLEKLADYPVPKSLGGLYLNATYLLGYG
FGDEYKVMGLAPWGNPETYRDTFAKLYTLQDNGEYELHGNIMVPNLVSPL
FYAEGFRPRRKGEPFTQAHRDFAAALQETVEKIVLHILEYWAKTSGHSRL
CFGGGVAHNSSLNGLILKSGLFDEVFVHPASHDAGAGEGAAYAAAASLGT
LERPGKRLLSASLGPALGGREQIRARLADWAPLIDVEFPDDAVETAAGLL
AEGQVLGWAYGRSEFGPRALGHRSIVADARPEENRTRINAMVKKREGFRP
FAPVVTAEAARDYFDLSGADGNHEFMSFVVPVLPERRTELGAVTHVDGTA
RVQVVSAESGERFHRLVRRFGELTGTPVLLNTSFNNNAEPIVQSLDDVVT
SFLTTDLDVLVVEDCLVRGKASPDLGVLVPRFRPVTRLVERRTAGPDASA
GAKTHEIHLDYDGGPSAKVSPELYELLGAVDGTTTLGDLAKTVGGLSDAL
ATEVFALWEQRFLTLAPAGDIGPL

3D structure

• PDB: 7vyp Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.
• Chain: B
• Resolution: 2.88 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	82Z	B	M242 V243 P244	M242 V243 P244
BS02	8CW	B	V24 F25 F26 H27 H87 V91 H94 D156 G157 R158 G187 Y190 L191 E204 G305 H308 N309 H332 D333	V24 F25 F26 H27 H87 V91 H94 D156 G157 R158 G187 Y190 L191 E204 G305 H308 N309 H332 D333
BS03	FE	B	H133 H137 D156 D333	H133 H137 D156 D333

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0005524 ATP binding
• GO:0046872 metal ion binding

Biological Process

• GO:0009058 biosynthetic process

External links

• PDB: RCSB:7vyp, PDBe:7vyp, PDBj:7vyp
• PDBsum: 7vyp
• PubMed: 36329057
• UniProt: Q84G19