Structure of PDB 7vw6 Chain B

Receptor sequence

>7vw6B (length=560) Species: 272630 (Methylorubrum extorquens AM1)

GTVRSFAHPGRGRNVARAVPKGRQVDPHAKVEIEELLGTRPRQRDLLIEH
LHLIQDTYGQISADHLAALADEMSLAFAEVFETATFYAHFDVVKEGEADI
PRLTIRVCDSITCAMFGADELLETLQRELASDAVRVVRAPCVGLCDHAPA
VEVGHNFLHRADLASVRAAVEAEDTHAHIPTYVDYDAYRAGGGYATLERL
RSGELPVDDVLKVLDDGGLRGLGGAGFPTGRKWRSVRGEPGPRLMAVNGD
EGEPGTFKDQLYLNTDPHRFLEGMLIGAHVVEAADVYIYLRDEYPISREI
LAREIAKLPEGGTRIHLRRGAGAYICGEESSLIESLEGKRGLPRHKPPFP
FQVGLFNRPTLINNIETLFWVRDLIERGAEWWKSHGRNGRVGLRSYSVSG
RVKEPGVKLAPAGLTIQELIDEYCGGISDGHSFAAYLPGGASGGILPASM
NDIPLDFGTLEKYGCFIGSAAVVILSDQDDVRGAALNLMKFFEDESCGQC
TPCRSGTQKARMLMENGVWDTDLLGELAQCMRDASICGLGQAASNPVSTV
IKYFPDLFPE

3D structure

• PDB: 7vw6 Multiple electron transfer pathways of tungsten-containing formate dehydrogenase in direct electron transfer-type bioelectrocatalysis.
• Chain: B
• Resolution: 2.19 Å

Enzymatic activity

• Enzyme Commision number: 1.2.1.2: Transferred entry: 1.17.1.9.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FES	B	C1134 T1138 C1139 C1167 L1170 C1171	C108 T112 C113 C141 L144 C145
BS02	SF4	B	I1351 P1369 S1522 C1523 G1524 Q1525 C1526 C1529 I1562 C1563 L1565 G1566	I325 P343 S496 C497 G498 Q499 C500 C503 I536 C537 L539 G540
BS03	FMN	B	G1247 G1249 K1258 N1274 D1276 Y1350 G1353 E1354 N1389 N1390 T1393	G221 G223 K232 N248 D250 Y324 G327 E328 N363 N364 T367

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0008137 NADH dehydrogenase (ubiquinone) activity
• GO:0010181 FMN binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0051537 2 iron, 2 sulfur cluster binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:1902600 proton transmembrane transport

External links

• PDB: RCSB:7vw6, PDBe:7vw6, PDBj:7vw6
• PDBsum: 7vw6
• PubMed: 35535582
• UniProt: C5ATT6