Structure of PDB 7vu0 Chain B

Receptor sequence

>7vu0B (length=435) Species: 83333 (Escherichia coli K-12)

GFIDDSTLTGGIYYWQRERDRKDVTDGDKYKTNLSHSTWNANLDFQSGYA
ADMFGLDIAAFTAIEMAENGDSSHPNEIAFSKSNKAYDEDWSGDKSGISL
YKAAAKFKYGPVWARAGYIQPTGQTLLAPHWSFMPGTYQGAEAGANFDYG
DAGALSFSYMWTNEYKAPWHLEMDEFYQNDKTTKVDYLHSFGAKYDFKNN
FVLEAAFGQAEGYIDQYFAKASYKFDIAGSPLTTSYQFYGTRDKVDDRSV
NDLYDGTAWLQALTFGYRAADVVDLRLEGTWVKADGQQGYFLQRMTPTYA
SSNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGFAIGASYVYAW
DAKPATWQSNPDAYYDKNRTIEESAYSLDAVYTIQDGRAKGTMFKLHFTE
YDNHSDIPSWGGGYGNIFQDERDVKFMVIAPFTIF

3D structure

• PDB: 7vu0 Chitoporin from Escherichia coli
• Chain: B
• Resolution: 1.85 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	DMU	B	S100 L101 Y119 K167 E173 M174	S99 L100 Y118 K166 E172 M173
BS02	C8E	B	T63 I65	T62 I64
BS03	C8E	B	A144 G145 A146 F158 Y160 H190	A143 G144 A145 F157 Y159 H189
BS04	C8E	B	Y237 F239	Y236 F238
BS05	C8E	B	G2 F3 A51 A52	G1 F2 A50 A51
BS06	C8E	B	A142 E143 A144 W162	A141 E142 A143 W161
BS07	C8E	B	N43 L44 F433	N42 L43 F432
BS08	C8E	B	H190 S191	H189 S190
BS09	C8E	B	A104 A105	A103 A104
BS10	C8E	B	Y268 A270 A271	Y267 A269 A270
BS11	C8E	B	F327 Y377	F326 Y376
BS12	C8E	B	E78 H131 W132 S133 W170 Y300	E77 H130 W131 S132 W169 Y299
BS13	MG	B	D403 N404 D421	D402 N403 D420
BS14	MG	B	P76 N77 E78 A80 D95	P75 N76 E77 A79 D94
BS15	MG	B	S231 R269 D272	S230 R268 D271

Gene Ontology

Molecular Function

• GO:0015267 channel activity
• GO:0015288 porin activity

Biological Process

• GO:0006811 monoatomic ion transport
• GO:0015772 oligosaccharide transport
• GO:0015774 polysaccharide transport
• GO:0052778 diacetylchitobiose metabolic process
• GO:0055085 transmembrane transport

Cellular Component

• GO:0009279 cell outer membrane
• GO:0016020 membrane
• GO:0046930 pore complex

External links

• PDB: RCSB:7vu0, PDBe:7vu0, PDBj:7vu0
• PDBsum: 7vu0
• UniProt: P75733|CHIP_ECOLI Chitoporin (Gene Name=chiP)