Structure of PDB 7vtg Chain B

Receptor sequence
>7vtgB (length=300) Species: 562 (Escherichia coli) [Search protein sequence]
EKDYVVIIGSANIDVAGYSHESDANPGKIKFTPGGVGRNIAQNLALLGNK
AWLLSAVGSDFYGQSLLTQTNQSGVYVDKCLIVPGENTSSYLSLLDEMLV
AINDMNISNAITAEYLAQHREFIQRAKVIVADCNISEEALAWILDNAANV
PVFVDPVSAWKCVKVRDRLNQIHTLKPNRLEAETLSGIALSGRDDVAKVA
AWFHQHGLNRLVLSMGGDGVYYSDIRGENGWSAPIKTNVINVTGAGDAMM
AGLASCWVDGMPFAESVRFAQGCSSMALSCEYTNNPDLSIANVISLVENA
3D structure
PDB7vtg Substrate-binding loop interactions with pseudouridine trigger conformational changes that promote catalytic efficiency of pseudouridine kinase PUKI.
ChainB
Resolution1.89859 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.83: pseudouridine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FJF B N14 D16 G40 G41 V42 N45 Y97 N112 M114 N143 K170 D256 N12 D14 G34 G35 V36 N39 Y91 N103 M105 N134 K161 D247
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0050225 pseudouridine kinase activity
Biological Process
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7vtg, PDBe:7vtg, PDBj:7vtg
PDBsum7vtg
PubMed35346685
UniProtP30235|PSUK_ECOLI Pseudouridine kinase (Gene Name=psuK)

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