Structure of PDB 7vro Chain B

Receptor sequence
>7vroB (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
TNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGT
IKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQ
KVASMPQ
3D structure
PDB7vro Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family.
ChainB
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 37T B P98 V103 N156 I162 P23 V28 N81 I87
External links
PDB RCSB:7vro, PDBe:7vro, PDBj:7vro
PDBsum7vro
PubMed37432115
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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