Structure of PDB 7vka Chain B

Receptor sequence
>7vkaB (length=589) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
SDESLAEKNKNKLQFIEDVTTNADDVQRRVLEEILSRNADVEYLKRHGLE
GRTDRETFKHIMPVVTYEDIQPEINRIANGDKSQVLCSNPISEFLTSSGT
SGGERKLMPTIEEELDRRSLLYSLLMPVMDQFVPGLDKGKGMYFLFIKSE
SKTPGGLPARPVLTSYYKSSHFKNRPYDPYTNYTSPNQTILCSDSYQSMY
SQMLCGLCQHKEVLRVGAVFASGFIRAIKFLEKHWPELARDIRTGTLSSE
ITDSSVREAVGEILKPDPKLADFVESECRKTSWQGIITRLWPNTKYVDVI
VTGTMSQYIPTLDYYSNGLPLVCTMYASSECYFGVNLRPLCKPSEVSYTL
IPNMAYFEFLPVHRNSGVTSSIKEQQELVDLVDVKLGQEYELVVTTYAGL
YRYRVGDVLSVAGFKNNAPQFSFICRKNVVLSIDSDKTDEVELQNAVKNA
VTHLVPFDASLSEYTSYADTSSIPGHYVLFWELCLNGNTPIPPSVFEDCC
LTIEESLNSVYRQGRVSDKSIGPLEIKMVESGTFDKLMDYAISLGASINQ
YKTPRCVKFAPIIELLNSRVVDSYFSPKCPKWSPGHKQW
3D structure
PDB7vka Chemical genetic screening identifies nalacin as an inhibitor of GH3 amido synthetase for auxin conjugation.
ChainB
Resolution2.401 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.3.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B S110 I312 T314 Y338 A339 S340 S341 Y360 D427 F443 R446 S98 I300 T302 Y326 A327 S328 S329 Y348 D407 F423 R426
BS02 7IS B Y134 Y178 Y195 I312 M337 A339 S340 Y122 Y166 Y183 I300 M325 A327 S328
Gene Ontology
Molecular Function
GO:0010279 indole-3-acetic acid amido synthetase activity
GO:0016874 ligase activity
Biological Process
GO:0009733 response to auxin
GO:0009734 auxin-activated signaling pathway
GO:0009826 unidimensional cell growth
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7vka, PDBe:7vka, PDBj:7vka
PDBsum7vka
PubMed36454752
UniProtQ9LSQ4|GH36_ARATH Indole-3-acetic acid-amido synthetase GH3.6 (Gene Name=GH3.6)

[Back to BioLiP]