Structure of PDB 7vjt Chain B

Receptor sequence
>7vjtB (length=272) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QIDGFVRTLRARPEAGGKVPVFVFHPAGGSTVVYEPLLGRLPADTPMYGF
ERVEGSIEERAQQYVPKLIEMQGDGPYVLVGWSLGGVLAYACAIGLRRLG
KDVRFVGLIDAVRAGEEIPQTKEEIRKRWDRYAAFAEKTFNVTIPAIPYE
QLEELDDEGQVRFVLDAVSIPAGIIEHQRTSYLDNRAIDTAQIQPYDGHV
TLYMADRYHDDAIMFEPRYAVRQPDGGWGEYVSDLEVVPIGGEHIQAIDE
PIIAKVGEHMSRALGQIEADRT
3D structure
PDB7vjt Structure-Based Optimization of Coumestan Derivatives as Polyketide Synthase 13-Thioesterase(Pks13-TE) Inhibitors with Improved hERG Profiles for Mycobacterium tuberculosis Treatment.
ChainB
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7IJ B Q1633 S1636 Y1637 N1640 R1641 I1643 D1644 A1667 F1670 Y1674 Q178 S181 Y182 N185 R186 I188 D189 A212 F215 Y219
Gene Ontology
Biological Process
GO:0009058 biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:7vjt, PDBe:7vjt, PDBj:7vjt
PDBsum7vjt
PubMed36174223
UniProtI6X8D2|PKS13_MYCTU Polyketide synthase Pks13 (Gene Name=pks13)

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