Structure of PDB 7va1 Chain B

Receptor sequence
>7va1B (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGIL
GLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCD
FITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQS
GQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEA
3D structure
PDB7va1 Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with GDD-04-35
ChainB
Resolution1.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.37: malate dehydrogenase.
1.1.1.399: 2-oxoglutarate reductase.
1.1.1.95: phosphoglycerate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5YP B L151 R158 Y174 D175 P176 I178 T207 T213 L216 L50 R57 Y73 D74 P75 I77 T106 T112 L115
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:7va1, PDBe:7va1, PDBj:7va1
PDBsum7va1
PubMed
UniProtO43175|SERA_HUMAN D-3-phosphoglycerate dehydrogenase (Gene Name=PHGDH)

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