Structure of PDB 7v3p Chain B

Receptor sequence
>7v3pB (length=816) Species: 9606 (Homo sapiens) [Search protein sequence]
EICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKARSYRFPKLTVITE
YLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNL
RNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCP
GCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAES
SDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKT
IDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKI
RHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLT
IKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCES
DVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRG
AKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIV
RWQRQPQDGYLYRHNYCSKDKIPIRKCACPKTEAEKQAEKEEAEYRKVFE
NFLHNSIFVPRPEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAE
KLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGL
ILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLS
GNGSWTDPVFFYVQAK
3D structure
PDB7v3p Cryo-EM structure of the IGF1R/insulin complex
ChainB
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B N698 P703 R704 N655 P660 R661
External links
PDB RCSB:7v3p, PDBe:7v3p, PDBj:7v3p
PDBsum7v3p
PubMed
UniProtP08069|IGF1R_HUMAN Insulin-like growth factor 1 receptor (Gene Name=IGF1R)

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