Structure of PDB 7v39 Chain B

Receptor sequence
>7v39B (length=206) Species: 11622 (Lassa virus Josiah) [Search protein sequence]
FTAGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCY
IHFFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVIT
CQGSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHT
GVVVEKGGKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRTS
TPRVVL
3D structure
PDB7v39 Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B E399 C506 H509 C529 E39 C146 H149 C166
BS02 HGB B Q379 C409 R551 Q19 C49 R188
External links
PDB RCSB:7v39, PDBe:7v39, PDBj:7v39
PDBsum7v39
PubMed34977900
UniProtP13699|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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