Structure of PDB 7uy4 Chain B

Receptor sequence
>7uy4B (length=257) Species: 562 (Escherichia coli) [Search protein sequence]
VIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDIDLLVTV
TVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYPAK
RELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELF
DPVPEQDLFEALNETLTLWNSPPDWAGDDRNVVLTLSRIWYSAVTGKIAP
KDVAADWAMERLPAQYQPVILEARQAYLGNEEDRLASRADQLEEFVHYVK
GEITKVV
3D structure
PDB7uy4 Characterization of the spectinomycin deactivating enzyme ANT-3,9
ChainB
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.47: streptomycin 3''-adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP B S32 S42 D43 D45 D126 I129 L130 K133 R188 K201 Y227 S32 S42 D43 D45 D126 I129 L130 K133 R188 K201 Y227
BS02 SMI B E83 W108 D178 N181 E83 W108 D178 N181
BS03 MG B D43 D45 D43 D45
BS04 MG B D43 D45 E83 D43 D45 E83
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0009012 aminoglycoside 3''-adenylyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0070566 adenylyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:7uy4, PDBe:7uy4, PDBj:7uy4
PDBsum7uy4
PubMed
UniProtP0AG05|S3AD_ECOLX Aminoglycoside (3'') (9) adenylyltransferase (Gene Name=aadA)

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