Structure of PDB 7uww Chain B

Receptor sequence

>7uwwB (length=627) Species: 657321 (Ruminococcus bromii L2-63)

SGSEAYFDNSKYGWKDVYVYAYGTKENAEWPGELMTKEDSGLYKASFASS
FKSEKIIFNNGLEKGNGKEQYPEAAGLSLKAGECKMLTAEKQWIDYGKPD
DHAYGYTLTANNTAFSTESLDVKLALKNADKGYYSVDGSAKKEFANGDSV
KVGEGKIGNSKVTLTLYATGADGVETEQTYTFKKTFTASKTTFSAKSDGH
TTAPESGYYGTNPEMQLGKHKTISVDGDLSDWDSSMIIAQGVANDDPRVY
MPSSMHEQPWDAYALYSAWDDDNLYFLLEMANTTYITSPEDNFAASNEAR
PWRNSIPMYLALSIDPAKQATGKAVGTNKDGSVYTNPFVWGCTDGGTGFT
THIDTLVAFDSNNSNGGASIFKADTQDTDGTYMFNYDTRIPIGVTSFQAQ
DNKNGFKIKYANGTKSTSIFGINAPKGSRVMGDNLDMNSNWVDFFDEGYK
NSYGYVYEIAVPLNTLGIDRSYIETQGIGAMQILTYGTSGMDTLPHDPSM
LDQANLEYSYDPSTSHEKEDIDNITVPLARIGALLPDTEVNEAPFEVNFG
ANLNSGQSAGTPITLLAESYHATGDVTYSFTVNGETVQNSNTDSCVWTPS
ADGTYSIGVVAVDANGNKAESTKTFVV

3D structure

• PDB: 7uww The Ruminococcus amylosome protein Sas6 binds single and double helical a-glucans structures in starch
• Chain: B
• Resolution: 1.61 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GLC	B	Y53 Y55 I90 A107	Y20 Y22 I57 A74
BS02	GLC	B	Y53 W63 K101 Q103	Y20 W30 K68 Q70
BS03	CA	B	V275 D278 D294 A295 D530	V242 D245 D261 A262 D492
BS04	CA	B	S527 G528 E555 D558 D560	S489 G490 E517 D520 D522
BS05	CA	B	S537 D540 E555 D558 D560	S499 D502 E517 D520 D522
BS06	CA	B	S257 D259 D261 D264 E496	S224 D226 D228 D231 E458

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding

Biological Process

• GO:0030245 cellulose catabolic process

External links

• PDB: RCSB:7uww, PDBe:7uww, PDBj:7uww
• PDBsum: 7uww
• PubMed: 38177679
• UniProt: A0A2N0UYM2